diff --git a/components/cascader/index.tsx b/components/cascader/index.tsx
index 676e7e95f3..17fc1dbbe5 100644
--- a/components/cascader/index.tsx
+++ b/components/cascader/index.tsx
@@ -292,7 +292,8 @@ class Cascader extends React.Component<CascaderProps, CascaderState> {
   };
 
   handleKeyDown = (e: React.KeyboardEvent<HTMLInputElement>) => {
-    if (e.keyCode === KeyCode.BACKSPACE) {
+    // SPACE => https://github.com/ant-design/ant-design/issues/16871
+    if (e.keyCode === KeyCode.BACKSPACE || e.keyCode === KeyCode.SPACE) {
       e.stopPropagation();
     }
   };